The Mercury Technological Center, is based at Cerco San Teodoro, in the former site of the Laboratory and Environment Area of Minas de Almadén y Arrayanes, S. A. The facilities were given to the Centre by said company and they comprise two buildings in the Almadén Historic Mining Complex, dating from the 1980s. They have been restored to form a single, fully refurbished building with a communications system that guarantees accessibility on every floor.

The building that houses the Centre covers an area of around 1500 m2. The four floors contain five laboratories, a sample preparation room, a sample and reagent warehouse, a library, training room, meeting room and offices.